This is likely naive and impractical since I’m a systems software engineer not a biochemist… but here goes:
Is anyone in the community interested in: https://en.wikipedia.org/wiki/Cellular_model and especially full cell models of simple unicellular organisms?
In particular, I’d like to carry out simulations / experiments of the type:
- in the simulation, you make up the cell genome / initial cell state
- let the simulation run and get some measurements that can be measured in practice, e.g.: how long until the cell doubles, what is the concentration of certain chemicals on growth medium, etc
- measure them on the lab, and see if model is good
This will likely require biological knowledge and measure / manipulation methods that haven’t been researched yet, super computers for the model, and full time work to get anywhere, but here goes my naive dream
If you have any such interesting cell simulations running on your computer, or open source software that actually works and is easy to get started with, let me know.